FIELD: chemical and pharmaceutical industry, colloidal chemistry, in particular production of blood substitutes with gas transmission function of tocopherol polyethylene glycol ester.
SUBSTANCE: invention relates to application of tocopherol polyethylene glycol ester application as surfactant to produce emulsion of perfluoroorganic compounds with gas transmission properties. Said emulsion contains 20 % of mixture of perfluoroorcanic compounds comprising perfluorodecaline and perfluoro-n-methylcyclohexyl piperidine in ratio of 2:1 and surfactant such as tocopherol polyethylene glycol ester or mixture thereof with proxanol. Method for production of abovementioned emulsion includes stabilizing of perfluorodecaline and perfluoro-n-methylcyclohexyl piperidine mixture with surfactant such as tocopherol polyethylene glycol ester or mixture thereof with proxanol, and emulsion is produced under homogenization pressure from 20 to 60 MPa with amount of homogenization cycles up to 30.
EFFECT: new blood substitutes with gas transmission function.
5 cl, 11 ex, 3 dwg
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Authors
Dates
2007-09-10—Published
2002-09-25—Filed