EMULSION OF PERFLUOROORGANIC COMPOUNDS WITH GAS TRANSMISSION PROPERTIES SURFACTANT OF SUCH EMULSION AND METHOD FOR PRODUCTION THEREOF Russian patent published in 2007 - IPC A61K31/355 A61K9/107 A61K31/25 A61K47/22 

Abstract RU 2305543 C2

FIELD: chemical and pharmaceutical industry, colloidal chemistry, in particular production of blood substitutes with gas transmission function of tocopherol polyethylene glycol ester.

SUBSTANCE: invention relates to application of tocopherol polyethylene glycol ester application as surfactant to produce emulsion of perfluoroorganic compounds with gas transmission properties. Said emulsion contains 20 % of mixture of perfluoroorcanic compounds comprising perfluorodecaline and perfluoro-n-methylcyclohexyl piperidine in ratio of 2:1 and surfactant such as tocopherol polyethylene glycol ester or mixture thereof with proxanol. Method for production of abovementioned emulsion includes stabilizing of perfluorodecaline and perfluoro-n-methylcyclohexyl piperidine mixture with surfactant such as tocopherol polyethylene glycol ester or mixture thereof with proxanol, and emulsion is produced under homogenization pressure from 20 to 60 MPa with amount of homogenization cycles up to 30.

EFFECT: new blood substitutes with gas transmission function.

5 cl, 11 ex, 3 dwg

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RU 2 305 543 C2

Authors

Kalinichenko Alla Nikolaevna

Kaptsov Vladimir Vasil'Evich

Lazarev Mikhail Ivanovich

Dates

2007-09-10Published

2002-09-25Filed