FIELD: biotechnology, in particular GHRH-fixing protein.
SUBSTANCE: disclosed is new protein having molecular mass of about 90.9 kDa which includes fragments of identified peptide sequences 1, 2 and 3. Method for production of said protein includes extraction of Pilocarpus heterophyllus plant cells with water, vacuum filtering, deposition of extracted proteins, centrifugation, and gel filtering of obtained filtrate. Also produced is monoclonal antibody which specifically fixes isolated protein.
EFFECT: agent for producing of effective drugs and pharmaceutical composition against GHRH action and treatment of proliferative diseases.
12 cl, 5 dwg, 2 ex
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Year |
Author |
Number |
| PLANT-ORIGINATED HETEROCARPINE PROTEIN HAVING ANTI-CANCER PROPERTIES |
2003 |
- Ferrandi Ehrik
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|
RU2317097C2 |
| METHOD FOR MAKING RECOMBINANT HETEROCARPINE |
2003 |
|
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| DERIVATIVES OF PROTEIN OB |
1996 |
- De Sovadzh Frederik Dzej
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|
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1998 |
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- Jasuda Khisataka
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- Sima Nobujuki
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- Tsuda Eisuke
- Goto Masaaki
- Jano Kazuki
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- Kobajasi Fumie
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- Morinaga Tomonori
- Khigasio Kandzi
|
RU2238949C2 |
| PROTEIN-HISTIDINE-PHOSPHATASE |
2000 |
- Zuzanne Klumpp
- Roland Kell'Ner
|
RU2281973C2 |
| USING DERIVATIVES OF CYSTEINE FOR PREPARING MEDICINAL AGENT DESIGNATED FOR TREATMENT OF PATHOLOGY ARISING AS RESULT OF FORMATION OF HETEROTRIMERIC PROTEIN G |
1999 |
- Prevo Greguar
- Lonsham Mari-Odil'
- Gordon Tomas
|
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| DISEASE-RELATED PROTEIN |
2002 |
- Levejar T'Erri
- Sael' Zhoze Alen
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|
RU2384586C2 |
| IMPROVED ANTI-IGE-ANTIBODY (VARIANTS) AND METHOD FOR IMPROVING POLYPEPTIDES |
1998 |
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| METHOD FOR PRODUCING CELASTROL AND PENTACYCLIC TRITERPENE DERIVATIVES |
2017 |
- Ngujen, Ten
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- Styuard, Nikolya
|
RU2743715C1 |
| EXTRACT OF UNDIFFERENTIATED Mimosa Pudica CELLS AND ITS APPLICATION IN DERMOCOSMETICS |
2017 |
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RU2747479C2 |
