FIELD: medicine, pharmacology and immunology.
SUBSTANCE: claimed vaccine includes polyanion matrix and peptide and Norbornene pharmacophor chemically bonded thereto. As polymer matrix vaccine contains polyanion matrix and as peptide it contains peptide mimetic of chimerical domain representing peptide fragment of p17/18/55 HIV-1/2 structural protein with CD4 cell receptor. Said vaccine has anti-viral, immunomodulating action and provide address delivery of complex vaccine preparation to site of HIV-1/2 infection and suppresses specific viral infection.
EFFECT: vaccine for prophylaxis and treatment HIV infection and AIDS.
1 dwg, 2 tbl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| COMPLEX OF MEMBRANOTROPIC COMPOUNDS FOR PROPHYLAXIS AND TREATMENT OF HIV-INFECTION | 2005 |
|
RU2315617C2 |
| COMPLEX ANTI-HIV COMPOUND | 2004 |
|
RU2270690C1 |
| VACCINE AGAINST HIV/AIDS | 2010 |
|
RU2475264C2 |
| HIV VACCINE BASED ON MAXIMISED Gag AND Nef TARGETING ON DENDRITE CELLS | 2009 |
|
RU2539765C2 |
| COMPOSITION USED FOR PROPHYLAXIS AND TREATMENT OF PATIENTS WITH AIDS OR SYSTEMIC LUPUS ERYTHEMATOSUS OR DISORDERS ASSOCIATED WITH SAID | 1995 |
|
RU2127599C1 |
| POLYANIONIC NORBORNAN DERIVATIVES, METHOD FOR PRODUCTION THEREOF AND REPRODUCTION INHIBITORS OF HUMAN IMMUNOGENICITY VIRUS BASED ON THE SAME | 2004 |
|
RU2281297C2 |
| PHARMACEUTICAL AGENT FOR TREATMENT OF HIV-INFECTION, COMPOSITION CONTAINING THEREOF AND METHODS FOR ITS USING | 2002 |
|
RU2290197C2 |
| NEW Tat-COMPLEXES AND VACCINES CONTAINING THEM | 2005 |
|
RU2432356C2 |
| RECOMBINANT VACCINE AGAINST HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 | 2006 |
|
RU2317107C2 |
| RECOMBINANT CHIMERICAL nTBI POLYPEPTIDE-IMMUNOGEN WITH ABILITY TO INDUCE NEUTRALIZING ANTIBODIES TO TYPE 1 HUMAN IMMUNODEFICIENCY VIRUS AND INTENDED FOR USE AS COMPONENT OF VACCINE AGAINST HIV-1 | 2016 |
|
RU2642258C1 |
