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2 475 264

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IPC

A61K39/395(2006-01-01)

C07K14/155(2006-01-01)

(21) (22)

Application

2010153928/10, 2010-12-29

(24)

Start date

2010-12-29

(22)

Actual filing date

2010-12-29

(45)

Published

2013-02-20

(72)

Inventor

Khaitov Rakhim MusaevichSidorovich Igor' GeorgievichNikolaeva Irina AleksandrovnaSheval'E Aleksandr FedorovichGasanov Vagif Ali-OglyIgnat'Eva Galina AlekseevnaKorobova Svetlana VjacheslavovnaGudima Georgij OlegovichKaramov Ehduard VladimirovichKornilaeva Galina VladimirovnaPavlova Tat'Jana VladimirovnaNekrasov Arkadij Vasil'EvichPuchkova Natal'Ja Grigor'EvnaMedvedev Sergej AlekseevichVazykhova Firuza Garunovna

(73)

Holder

Federal'Noe Gosudarstvennoe Bjudzhetnoe Uchrezhdenie Nauchnyj Tsentr Immunologii" Federal'Nogo Mediko-Biologicheskogo Agentstva

VACCINE AGAINST HIV/AIDS Russian patent published in 2013 - IPC A61K39/395 C07K14/155

Abstract RU 2475264 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to field of biotechnology, virology and medicine. Vaccine against HIV/AIDS, includes compound of vaccine antigens of HIV/AIDS virus and pharmacologically acceptable carrier. As vaccine antigens of HIV/AIDS virus applied is chimeric recombinant polypeptide, copying immunoactive areas of three HIV1 proteins - fragment of transmembrane protein gp41, coded by gen env, full-size recombinant protein p24, coded by gen gag, and fragment of internal protein p17, coded by gen gag. As polymer carrier applied is derivative of heterochain polyamines with molecular weight 50000-150000D at ratio 1:10.

EFFECT: invention presence safe vaccine against HIV/AIDS, which has high immunogenic activity and antigen specificity.

4 dwg, 4 tbl, 17 ex

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RU 2 475 264 C2

Authors

Khaitov Rakhim Musaevich

Sidorovich Igor' Georgievich

Nikolaeva Irina Aleksandrovna

Sheval'E Aleksandr Fedorovich

Gasanov Vagif Ali-Ogly

Ignat'Eva Galina Alekseevna

Korobova Svetlana Vjacheslavovna

Gudima Georgij Olegovich

Karamov Ehduard Vladimirovich

Kornilaeva Galina Vladimirovna

Pavlova Tat'Jana Vladimirovna

Nekrasov Arkadij Vasil'Evich

Puchkova Natal'Ja Grigor'Evna

Medvedev Sergej Alekseevich

Vazykhova Firuza Garunovna

Dates

2013-02-20—Published

2010-12-29—Filed