POLYSACCHARIDE FROM ECHINACEA ANGUSTIFOLIA ROOTS, METHOD FOR PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITION Russian patent published in 2007 - IPC C08B37/00 C08B37/18 A61K31/715 A61P37/00 

FIELD: biochemistry.

SUBSTANCE: invention relates to polysaccharide from Echinacea angustifolia roots with molecular mass of 1.3x10⁹ Da and comprising of ramnose, arabinose, galactose, and galacturonic acid in ratio of 0.5:2.5:1.75:10.25. Said polysaccharide has skeleton with linear and branched repeated units, wherein linear units comprise partially acetylated and methylated galacturonic acid residues bonded via α-(1-4) bonds and branched units comprise repeated units of galacturonic acid residues and ramnose bearing side chains comprising arabinose and galactose in ratio of 2.5:1.75. Said polysaccharide is useful in production of drug for amplification of immune system. Method for production of polysaccharide includes removing of non-polysaccharide components from Echinacea angustifolia roots by extraction with solvent such as acetone or C₁-C₃-alcohol containing not more than 40 % v/v of water; extraction of polysaccharide fraction from Echinacea angustifolia roots directly obtained in the first stage with solvent such as water or mixture of water and acetone, or water and C₁-C₃-alcohol containing at least 60 % of water; polysaccharide isolating by chromatography from polysaccharide fraction obtained after preliminary purification.

EFFECT: new polysaccharide with pharmaceutical properties.

16 cl, 2 tbl, 4 ex