METHOD FOR PREPARING ADAMANTYL-CONTAINING AROMATIC COMPOUNDS Russian patent published in 2007 - IPC C07C13/615 

FIELD: organic chemistry, chemical technology.

SUBSTANCE: invention relates to a method for synthesis of adamantyl-containing aromatic compounds of the general formula: , wherein R¹ = R² = R³ = R⁴ means hydrogen atom (H); R⁵ means Ad (1); R¹ means -CH₃; R² = R³ = R⁵ means H; R⁴ means Ad (2); R¹ means -C₂H₅; R² = R³ = R⁵ means H; R⁴ means Ad (3); R¹ means i-C₃H₇; R² = R³ = R⁵ means H; R⁴ means Ad (4); R¹ = R² means -CH₃; R³ = R⁵ means H; R⁴ means Ad (5); R¹ = R³ means -CH₃; R² = R⁵ means H; R⁴ means Ad (6); R¹ = R⁴ means -CH₃; R² = R³ means H; R⁵ means Ad (7) that are intermediate products for synthesis of biologically active substances. Method involves adding aromatic compounds to a adamantine derivative wherein 1,3-dehydroadamantane is used as a adamantine derivative, and compounds chosen from the following order: benzene, toluene, ethylbenzene, isopropylbenzene (cumene), o-, m-, p-xylene are used as aromatic compounds in the mole ratio of reagents = 1:(2-4) in diethyl ether medium, at temperature 30-35°C, or in the parent aromatic compound medium at their boiling point (80-110°C) for 30 min, in the presence of catalytic amounts of sulfuric acid. Method provides preparing the claimed compounds with the high yield.

EFFECT: improved method of synthesis.

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