FIELD: organic chemistry, chemical technology. SUBSTANCE: invention relates to derivatives of adamantine, namely to a novel method of synthesis of β-dicarbonyl derivatives of adamantine of the general formula: 
where R is CH3:R1-CH3,OC2H5; R is C6H5:R1-OC2H5,C6H5,CF2H; R is CF3:R1-C6H5,n-C6H4Cl; 
that are products used for synthesis of biologically active substances. Compounds are synthesized by interaction of 1,3-dehydroadamantane with corresponding β-diketone or ketoester in the mole ratio of reagents = 1 : (1.5-2) in diethyl ether medium as an inert solvent, at its boiling point for 1-3 h. The yield of end compounds is 81-98%. EFFECT: simplified method, high yield. 11 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF SYNTHESIS OF α-ADAMANTYL-CONTAINING ALIPHATIC AND SATURATED AROMATIC KETONES | 2000 |
|
RU2186760C2 |
| METHOD FOR PREPARING ADAMANTYL-CONTAINING NITRILES | 2003 |
|
RU2240310C1 |
| METHOD FOR PREPARING N-PHTHALIMIDOALKYLADAMANTANE OR ITS DERIVATIVES | 2003 |
|
RU2247114C1 |
| METHOD FOR PREPARING ADAMANTYL-CONTAINING AROMATIC COMPOUNDS | 2006 |
|
RU2309932C1 |
| METHOD OF PRODUCING ADAMANTYL ESTERS OF UNSATURATED ACIDS | 2010 |
|
RU2448950C1 |
| METHOD OF OBTAINING ADAMANTYL CONTAINING DERIVATIVES OF 1,4-DIKETONES | 2006 |
|
RU2330013C1 |
| METHOD OF OBTAINING ADAMANTYL CONTAINING PHENOL DERIVATIVES | 2006 |
|
RU2326104C1 |
| METHOD FOR PREPARING ADAMANTYL-CONTAINING DERIVATIVES OF NAPHTHALENE | 2006 |
|
RU2309933C1 |
| METHOD OF SYNTHESIS OF ADAMANT-1-YLAMINE AND ITS DERIVATIVES | 1998 |
|
RU2147573C1 |
| METHOD FOR PREPARING ALPHA-ADAMANTYL-CONTAINING ALDEHYDES | 2003 |
|
RU2240303C1 |
