METHOD OF OBTAINING ADAMANTYL CONTAINING PHENOL DERIVATIVES Russian patent published in 2008 - IPC C07C13/615 

FIELD: chemistry.

SUBSTANCE: invention pertains to the method of obtaining adamantyl containing phenol derivatives with general formula , where R¹=R²=R⁴=H, R₃=Ad (I); R¹=CH₃, R²=R⁴=H, R³=Ad (II); R¹=Ad, R²=R³=H, R⁴=CH₃(III); R¹=Ad, R²=R⁴=H, R³=CH₃(IV); R¹=OH, R²=R⁴=H, R³=Ad (V); R¹=Ad, R²=R³=H, R⁴=OH(VI); R¹=Ad, R²=R⁴=H, R³=OH (VII), which are intermediate products during synthesis of biologically active substances. The method lies in that, the adamantane derivative is subjected to interaction with aromatic compounds at reagent molar ratios of 1:(1.5-2) in medium of diethyl ether at its boiling temperature for a period of 20-30 min. in the presence of catalyst quantities of sulphuric acid. The adamantane derivative used is 1,3-dehydroadamantane. The aromatic compound used is chosen from: phenol, o- , m-, p-cresol, pyrocatechol, resorcin, and hydroquinone.

EFFECT: invention enables design of a less-staged method, which allows to obtain a wide range of chemical compounds with high output.

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