METHOD FOR PREPARING (ADAMANT-1-YLMETHYLENE)-CONTAINING AROMATIC COMPOUNDS Russian patent published in 2007 - IPC C07C13/615 

FIELD: organic chemistry, chemical technology.

SUBSTANCE: invention relates to chemistry of adamantine derivatives, namely, to a novel method for synthesis of (adamant-1-ylmethylene)-containing aromatic compounds of the general formula (I): , wherein R¹ = R² = R³ = R⁴ means hydrogen atom (H) (1); R¹ means -CH₃; R² = R³ = R⁴ means H (2); R¹ = R³ = R⁴ means H; R² means -CH₃ (3); R¹ = R² = R⁴ means H; R³ means -CH₃ (4); R¹ = R² means H; R² = R⁴ means -CH₃ (5); R¹ = R³ = R⁴ means -CH₃; R² means H (6); Ad means 1-adamantyl that are intermediate products for synthesis of biologically active substances. Method involves adding aromatic compounds to adamantine derivative wherein 1,3-dehydroadamantane is used as a adamantine derivative, and the following compounds are used as aromatic compounds: toluene, o-, m-, p-xylene, mesitylene, durene in the mole ratio of reagent = 1:(2-4) in the parent aromatic compound medium, at their boiling point (110-197°C) for 60 min. Invention provides simplifying method for synthesis of abovementioned compounds and their synthesis with higher yields.

EFFECT: improved methods of synthesis.

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