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(19)

(11)

2 310 663

(13)

(51)

IPC

C07K17/04(2006-01-01)

(21) (22)

Application

2006109913/13, 2006-03-29

(24)

Start date

2006-03-29

(22)

Actual filing date

2006-03-29

(45)

Published

2007-11-20

(72)

Inventor

Ovchinnikov Maksim MaksimovichPakhomov Pavel MikhajlovichKhizhnjak Svetlana Dmitrievna

(73)

Holder

Obshchestvo S Ogranichennoj Otvetstvennost'Ju

METHOD FOR PREPARING LIPOSOME COMPOSITION WITH GEL SYNTHESIZED FROM CYSTEINE AND SILVER NITRATE Russian patent published in 2007 - IPC C07K17/04

Abstract RU 2310663 C1

FIELD: biotechnology, chemical technology.

SUBSTANCE: invention relates to a method for preparing liposome-containing compiositions. Method involves placing phosphatidylcholine in an organic solvent into rotor evaporator and solvent is distilled off to obtain phospholipid film on rotor evaporator flask walls. Then film is transferred to aqueous dispersion and liposomes containing incorporated additive are prepared. Then aqueous dispersion of liposomes is subjected for dialysis and an aqueous solution containing gel-forming components is added. Ethyl alcohol is used as an organic solvent. Solvent is distilled off at 40^oC and phospholipid film is transferred to dispersion in a shaking device. Cysteine and silver nitrate are used as gel-forming components. Invention provides excluding using toxic organic solvent, elimination of sterilization of liposome dispersion and addition of special antibacterial additives to the ready preparation. Invention can be used in medicinal and cosmetic practice.

EFFECT: improved preparing method.

2 dwg, 1 ex

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RU 2 310 663 C1

Authors

Ovchinnikov Maksim Maksimovich

Pakhomov Pavel Mikhajlovich

Khizhnjak Svetlana Dmitrievna

Dates

2007-11-20—Published

2006-03-29—Filed