FIELD: medicine.
SUBSTANCE: method involves determining marked γ-interferon response to stimulation with specific H37Rv in patients having asymptomatic course and limited active lung tuberculosis in comparison to patients having inactive cured changes in lungs. Difference between induced and spontaneous γ-interferon production in 48 h old culture supernatants from 10-fold diluted venous blood being equal to 60-1400 pg/ml, active tuberculosis is diagnosed. The value being equal to 0-50 pg/ml, lack of tuberculous process is diagnosed.
EFFECT: high accuracy and specificity of diagnostic tests.
2 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| DIAGNOSTIC TECHNIQUE FOR TUBERCULOSIS INFECTION | 2014 |
|
RU2560679C1 |
| METHOD FOR ASSESSING TUBERCULOSIS ACTIVITY IN CHILDREN AND ADOLESCENTS | 2011 |
|
RU2498311C2 |
| RECOMBINANT PLASMID DNA pTB323 CODING HYBRID POLYPEPTIDE CST-DELTAMPT64 WITH PROPERTIES OF SPECIES-SPECIFIC MYCOBACTERIAL ANTIGEN MPT64 (MPB64), RECOMBINANT ESCHERICHIA COLI BACTERIAL STRAIN - PRODUCER OF HYBRID POLYPEPTIDE CST-DELTAMPT64 AND RECOMBINANT POLYPEPTIDE CST-DELTAMPT64 | 2011 |
|
RU2458130C1 |
| METHOD FOR EVALUATING ACTIVITY OF TUBERCULOSIS INFECTION IN CHILDREN AND ADOLESCENTS | 2015 |
|
RU2586279C1 |
| DIAGNOSTIC TECHNIQUE FOR PULMONARY TUBERCULOSIS | 2012 |
|
RU2503005C1 |
| METHOD FOR ASSESSING POSTVACCINAL IMMUNITY AGAINST BRUCELLOSIS | 2019 |
|
RU2740009C1 |
| RECOMBINANT PLASMIDE ENCODING HYBRID GST-ESAT-6 POLYPEPTIDE HAVING ACTIVITIES OF SPECIES-SPECIFIC MYCOBACTERIAL ESAT-6 ANTIGEN, RECOMBINANT ESCHERICHIA COLI STRAIN AS PRODUCER OF HYBRID GST-ESAT-6 POLYPEPTIDE AND RECOMBINANT GST-ESAT-6 POLYPEPTIDE | 2004 |
|
RU2282661C2 |
| METHOD FOR DETERMINING SPECIFIC SENSITIZATION OF LYMPHOCYTES TO TOXOPLASM | 2022 |
|
RU2797361C1 |
| METHOD FOR IMMUNOLOGICAL DETERMINATION OF TUBERCULOSIS INFECTION ACTIVITY IN CHILDREN AND ADOLESCENTS WITH LATENT INFECTION | 2020 |
|
RU2726789C1 |
| DIAGNOSTIC TECHNIQUE FOR TUBERCULOSIS INFECTION | 2012 |
|
RU2503006C1 |
