FIELD: medicine.
SUBSTANCE: specific cell-mediated immunity is assessed by modified lymphocyte blast transformation reaction (mLBTR) with PPD-L tuberculine; the level of interferon-gamma (IFN-γ) with PPD-L is tested with using a small volume (200 mcl) of whole blood and 4 dilutions of the PPD-L antigens. If the cell immunity stimulation index is more than 3.2 and IFN-γ with PPD-L more than 7.0, an active tuberculosis process, while the mLBTR with PPD-L more than 3.2 and IFN-γ with PPD-L less than 7.0 show an inactive tuberculosis infection.
EFFECT: using the given method enables more specific diagnosis of the tuberculosis infection, and assessed effectiveness of the conducted treatment.
2 ex
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Authors
Dates
2013-11-10—Published
2011-03-21—Filed