METHOD FOR ASSESSING TUBERCULOSIS ACTIVITY IN CHILDREN AND ADOLESCENTS Russian patent published in 2013 - IPC G01N33/53 

Abstract RU 2498311 C2

FIELD: medicine.

SUBSTANCE: specific cell-mediated immunity is assessed by modified lymphocyte blast transformation reaction (mLBTR) with PPD-L tuberculine; the level of interferon-gamma (IFN-γ) with PPD-L is tested with using a small volume (200 mcl) of whole blood and 4 dilutions of the PPD-L antigens. If the cell immunity stimulation index is more than 3.2 and IFN-γ with PPD-L more than 7.0, an active tuberculosis process, while the mLBTR with PPD-L more than 3.2 and IFN-γ with PPD-L less than 7.0 show an inactive tuberculosis infection.

EFFECT: using the given method enables more specific diagnosis of the tuberculosis infection, and assessed effectiveness of the conducted treatment.

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RU 2 498 311 C2

Authors

Patsula Jurij Ivanovich

Plekhanova Marija Aleksandrovna

Mordyk Anna Vladimirovna

Glinskikh Ol'Ga Sergeevna

Dates

2013-11-10Published

2011-03-21Filed