FIELD: molecular biology, bioorganic chemistry, biochemistry.
SUBSTANCE: method for preparing DNA-chips involves immobilization of an oligonucleotide containing a terminal nucleophilic group on polymer surface treated with metal hydroxide solutions of different concentration. Immobilization of oligonucleotide is carried out both in the presence and absence of a condensing agent. Using the invention provides preparing DNA-chips of high quality.
EFFECT: improved preparing method of DNA-chips.
18 cl, 1 tbl, 8 dwg, 11 ex
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