FIELD: organic chemistry, medicine, pharmacy.
SUBSTANCE: invention describes compounds of the formula (I): wherein R1-R5 mean independently of one another (C0-C30)-alkylene-(LAG)n wherein n = 1, and one or some C-atoms in alkylene residue can be replaced for -O-, -(C=O)-, -C=CH-, -NH-, hydrogen atom (H), fluorine atom (F), chlorine atom (Cl), bromine atom (Br), iodine atom (J), (C1-C6)-alkyl, O-(C1-C6)-alkyl; (LAG)n means mono- or tricyclic trialkyl ammoniumalkyl residue or LAG can mean -(CH2)0-10-C(=NH)(NH2), -(CH2)0-10-C(=NH)(NHOH) or -NR7-C(=NR8)(NR9R10). Also, invention describes a medicinal agent for decreasing the serum cholesterol content and a method for its preparing. Proposed compounds are useful, for example, as hypolipidemic agents.
EFFECT: improved methods of synthesis and preparing, valuable medicinal properties of compounds and pharmaceutical composition.
6 cl, 1 tbl, 34 ex
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Authors
Dates
2008-01-27—Published
2003-06-04—Filed