METHOD FOR PRODUCTION OF BLOCK-COPOLYMER-DRUG COMPOSITE Russian patent published in 2008 - IPC A61K9/127 A61K9/19 A61K47/30 A61K31/704 A61K47/34 A61K47/48 A61P35/00

Abstract RU 2316314 C2

FIELD: pharmaceuticals.

SUBSTANCE: claimed method includes step of dissolution of AB-type block-copolymer, comprising hydrophilic polymer structure unit representing polyethylene oxide derivatives and hydrophobic polyamino acid structure fragment representing polyasparaginic acid together with drug (doxorubicine or salt thereof) in mixed solvent containing water and low boiled water miscible organic solvent followed by concentration of obtained solution.

EFFECT: new block-copolymer-drug composite.

4 cl, 2 tbl, 3 ex

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RU 2 316 314 C2

Authors

Nakanisi Takesi

Simizu Kazukhisa

Dates

2008-02-10—Published

2003-06-18—Filed