FIELD: medicine, laboratory diagnostics.
SUBSTANCE: after blood sampling one should simultaneously detect the subclasses of immunoglobulins IgG-3 and IgG-4 due to fulfilling modified complement binding reaction (m-CBR) and detect the level of antibodies IgG due to immunoenzymatic assay (IEA). At the presence of antibodies in m-CBR in subclass IgG-3 in titers being 1:10-1:80 and the level of antibodies IgG in IEA in titer being >200 IU/ml one should establish acute form of the disease mentioned. At the presence of antibodies in m-CBR in subclass IgG-4 in titers being 1:20-1:50 and the level of antibodies IgG in IEA being <200 IU/ml one should state upon chronic form of the disease.
EFFECT: higher accuracy of diagnostics.
3 ex, 2 tbl
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