METHOD FOR DIFFERENTIAL DIAGNOSTICS OF HYPERPLASIA, INTRAEPITHELIAL NEOPLASIAS AND CERVIX UTERI CANCER Russian patent published in 2008 - IPC G01N33/483 

FIELD: medicine.

SUBSTANCE: the present innovation refers to the methods of cytological diagnostics. Smears obtained out of cervix uteri canal should be dyed with nuclear dye to be then studied upon a computed analyzer. On the image obtained it is necessary to measure the area of the nuclei of normal and tumor cells to establish their average values, moreover, the average value of the area of the nuclei of normal cells should be considered to be the standard. Then one should determine the multiplicity of excessive average value of the nuclei of tumor cells against the standard and at the value of this parameter ranged 1.1-1.4 times - one should diagnose hyperplasia, at 1.5-1.9 times - cervical intraepithelial neoplasia degree I (benign stage of carcinogenesis), at 2.0-2.4 times - cervical intraepithelial neoplasia stage II (boundary stage of carcinogenesis), and at its value being 2.5 and higher - cervix uteri cancer (malignant stage of carcinogenesis). The innovation enables to carry out accurate objective differential diagnostics of carcinogenesis stages in cervix uteri upon any cytological preparations.

EFFECT: higher accuracy and efficiency of diagnostics.

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