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(11)

2 325 915

(13)

(51)

IPC

A61K33/08(2006-01-01)

A61K51/12(2006-01-01)

A61P9/00(2006-01-01)

(21) (22)

Application

2002116354/14, 2002-06-17

(24)

Start date

2002-06-17

(22)

Actual filing date

2002-06-17

(45)

Published

2008-06-10

(72)

Inventor

Mukhamadijarov Rinat AvkhadievichBarbarash Leonid SemenovichZhuravleva Irina Jur'EvnaKhaliulin Igor' Germanovich

(73)

Holder

Gosudarstvennoe Uchrezhdenie Nauchno-Proizvodstvennaja Problemnaja Laboratorija Rekonstruktivnoj Khirurgii Serdtsa I Sosudov S Klinikoj So Ramn

METHOD OF ISOLATED HEART ISHEMIC AND REPERFUSION INJURIES PREVENTION Russian patent published in 2008 - IPC A61K33/08 A61K51/12 A61P9/00

Abstract RU 2325915 C2

FIELD: medicine.

SUBSTANCE: invention refers to medicine, specifically to cardiovascular surgery and can be applied within heart surgical procedures experimentally. For this purpose perfusion is retrograde conducted through aortic cannula with oxygenated solution at first and then with non-oxygenated solution combined with liposome addition under specified conditions. Method provides restoration of contractile function and heart rhythm due to liposomic stabilisation of cell membranes and reduction of lipid peroxidation product.

EFFECT: restoration of contractile function and heart rhythm.

2 cl, 2 ex

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RU 2 325 915 C2

Authors

Mukhamadijarov Rinat Avkhadievich

Barbarash Leonid Semenovich

Zhuravleva Irina Jur'Evna

Khaliulin Igor' Germanovich

Dates

2008-06-10—Published

2002-06-17—Filed