2,5-SUBSTITUTED TETRAHYDROISOQUINOLINE AND A PHARMACEUTICAL MODULATION COMPOSITION 5-НТ6 Russian patent published in 2008 - IPC C07D217/24 C07D401/12 C07D217/08 A61K31/472 A61P25/00

Abstract RU 2327689 C2

FIELD: organic chemistry.

SUBSTANCE: description is given of compounds with formula (I) and their pharmaceutical salts, in which n, X, Y, R¹, R², R³, R⁴ and R⁵ are defined in this invention. The obtained compounds have modulating action relative to "5-НТ6" receptors. Description is also given of a pharmaceutical composition based on compounds with formula (I), used as "5-НТ6" modulators for treating damages to the central nervous system.

EFFECT: obtaining of new compounds, with useful biological properties.

10 cl, 1 tbl, 5 ex

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RU 2 327 689 C2

Authors

Putman Dejvid Dzhordzh

Dates

2008-06-27—Published

2004-02-23—Filed