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(19)

(11)

2 388 748

(13)

(51)

IPC

C07C235/34(2006-01-01)

C07C211/42(2006-01-01)

C07C217/48(2006-01-01)

C07D211/58(2006-01-01)

C07C317/32(2006-01-01)

A61K31/10(2006-01-01)

A61K31/131(2006-01-01)

A61K31/132(2006-01-01)

A61K31/4468(2006-01-01)

A61P25/00(2006-01-01)

(21) (22)

Application

2007122406/04, 2005-12-12

(24)

Start date

2005-12-12

(22)

Actual filing date

2005-12-12

(45)

Published

2010-05-10

(72)

Inventor

Kharris Ral'F N'Ju IiiKrauss Nensi EhlizabetKress Dzhejms M.Repke Devid BrjusStabler Rassell Stefen

(73)

Holder

F. Khoffmann-Lja Rosh Ag

TETRALIN AND INDANE DERIVATIVES AND USE THEREOF AS 5-HT ANTAGONISTS Russian patent published in 2010 - IPC C07C235/34 C07C211/42 C07C217/48 C07D211/58 C07C317/32 A61K31/10 A61K31/131 A61K31/132 A61K31/4468 A61P25/00

Abstract RU 2388748 C2

FIELD: chemistry.

SUBSTANCE: described is a compound of formula

or its pharmaceutically acceptable salt, where m, p, q, Ar, R¹ and R² are as given in the description, as well as a pharmaceutical composition with selective affinity to 5-HT receptors which contains a formula (I) compound.

EFFECT: obtained compounds have selective affinity to 5-HT receptors and can be used, as expected, in treating certain central nervous system disorders.

21 cl, 1 tbl, 6 ex

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RU 2 388 748 C2

Authors

Kharris Ral'F N'Ju Iii

Krauss Nensi Ehlizabet

Kress Dzhejms M.

Repke Devid Brjus

Stabler Rassell Stefen

Dates

2010-05-10—Published

2005-12-12—Filed