METHOD OF DIAGNOSTICS OF ORGANISM SYSTEM INFLAMMATORY RESPONSE FOR CRITICAL STATES Russian patent published in 2008 - IPC A61B10/00 G01N33/48 

Abstract RU 2328219 C1

FIELD: medicine.

SUBSTANCE: peripheral blood lymphocytes are released by density gradient, impaired membrane-cytoskeleton interrelations within lymphocytes are detected using phase-contrast microscopy, impaired lymphocytic plasma membrane evidence is registered during blebbing, lymphocytic blebbing index value and total lymphocytic blebbing are calculated, so that total blebbing is calculated by addition of lymphocytes during initial blebbing, characterised by small vesicles on membrane up to 1/3 of cell radius and lymphocytes during thermal blebbing characterised by large bubbles on membrane surface more than 1/3 of cell radius, lymphocytic blebbing index is calculated by multiplication of a lymphocytes during thermal blebbing by 100 divided by total lymphocytic blebbing. And in case total lymphocytic blebbing is increased by 30%, and lymphocytic blebbing index value is more than 37 standard units, organism system inflammatory response for critical states is diagnosed.

EFFECT: method provides optimised diagnostics of organism system inflammatory response for critical states.

3 tbl, 3 dwg, 2 ex

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Authors

Fursov Aleksandr Anatol'Evich

Salmina Alla Borisovna

Mikhutkina Svetlana Valer'Evna

Malinovskaja Natalija Aleksandrovna

Sokolovich Aleksej Georgievich

Linev Kirill Aleksandrovich

Beljaev Kirill Jur'Evich

Uspenskaja Julija Aleksandrovna

Inzhutova Alena Ivanovna

Danilovich Aleksandr Vladimirovich

Gajgol'Nik Denis Valer'Evich

Ehjdemiller Nina Sergeevna

Zin'Kovskaja Svetlana Jur'Evna

Dates

2008-07-10Published

2007-03-12Filed