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2 328 502

(13)

(51)

IPC

C07H9/02(2006-01-01)

C07H9/04(2006-01-01)

A61K31/7004(2006-01-01)

A61P25/08(2006-01-01)

A61P25/00(2006-01-01)

(21) (22)

Application

2004133334/04, 2003-05-09

(24)

Start date

2003-05-09

(22)

Actual filing date

2003-05-09

(45)

Published

2008-07-10

(72)

Inventor

Abdel'-Magid AkhmedMarianoff SintijaMermehn StivenSordzhi KirkVillani FrehnkKordik Cheril P.Rejtts Allen B.Marianoff Brjus Ehliot

(73)

Holder

Orto-Maknejl Farmas'Jutikal, Ink.

NOVEL ANTICONVULSIVE SUBSTITUTED SULFAMATE DERIVATIVES Russian patent published in 2008 - IPC C07H9/02 C07H9/04 A61K31/7004 A61P25/08 A61P25/00

Abstract RU 2328502 C2

FIELD: chemistry.

SUBSTANCE: invention relates to the novel compounds with formula (I): where the values for X, R¹, R², R³, R⁴, R⁵, R⁶ are indicate in section 1 of the invented formula with anticonvulsive activity; and to their pharmaceutical compositions. The invention also relates to the method for producing the intermediate compounds with formula (XX) where the values for X, R³, R⁴, R⁵, R⁶ are indicate the invented formula; and to the method for treating epilepsy with use of the therapeutically effective amount of the invented compound.

EFFECT: anticonvulsive activity.

31 cl, 7 dwg, 23 ex

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RU 2 328 502 C2

Authors

Abdel'-Magid Akhmed

Marianoff Sintija

Mermehn Stiven

Sordzhi Kirk

Villani Frehnk

Kordik Cheril P.

Rejtts Allen B.

Marianoff Brjus Ehliot

Dates

2008-07-10—Published

2003-05-09—Filed