FIELD: medicine.
SUBSTANCE: group of inventions refers to delivery system for antigen as T-cell, containing, at least, one antigen and loading antigen-presenting cells with specified antigen. Application of T-cell containing at least one antigen is offered in medical product for antigen delivery to lymph node. Application of antigen associated with T-cell containing at least one other antigen causing immune response is offered in medical product for immune response monitoring against at least one other antigen. Application of T-cell containing at least one antigen is offered in medical product for antigen-presenting cells (APC) loading with antigen.
EFFECT: offered method of T-cell production for application under any item mentioned above, including T-cell isolation, T-cell activation, T-cell cultivation and antigen introduction to T-cell, where T-cell is transduced with antigen.
24 cl, 8 ex, 1 tbl, 7 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| METHODS OF EX VIVO EXPANSION OF NATURAL KILLER CELLS AND THEIR USE | 2019 |
|
RU2814083C2 |
| METHODS OF EXPANSION OF ANTIGEN-SPECIFIC CAR-T-CELLS, COMPOSITIONS AND THEIR USE | 2019 |
|
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| CHIMERIC ANTIGENIC RECEPTORS WITH MND-PROMOTER | 2015 |
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| THERAPEUTIC COMPOSITIONS AND METHODS OF USING FOR TREATING CANCER | 2016 |
|
RU2720984C2 |
| ANTIGEN RECEPTORS AND THEIR APPLICATIONS | 2016 |
|
RU2792042C2 |
| CHIMERIC ANTIGENIC RECEPTORS WITH MND PROMOTER | 2015 |
|
RU2799573C2 |
| ANTIGEN RECEPTORS AND THEIR APPLICATIONS | 2018 |
|
RU2794945C2 |
| MHC DISPLAY OF MAMMALIAN PEPTIDES AS A TOOL FOR THE SELECTION OF ANTIGENIC DETERMINANTS IN THE CREATION OF VACCINES | 2019 |
|
RU2795983C2 |
| MODIFIED MONOCYTES/MACROPHAGES EXPRESSING CHIMERIC ANTIGEN RECEPTORS AND THEIR APPLICATIONS | 2016 |
|
RU2766690C2 |
| VACCINE BASED ON B-CELLS, LOADED WITH LIGANDS OF T-CELLS-NATURAL KILLERS AND ANTIGEN | 2006 |
|
RU2420311C2 |
