METHOD FOR OBTAINING 6α, 9α-DIFLUOR- 17α-(1-OXO-PROPOXY)-11β-HYDROXY-16α-METHYL-3-OXO-ANDROST-1,4-DIENE-17β-CARBOTHIONE ACID Russian patent published in 2008 - IPC C07J31/00 

Abstract RU 2333217 C2

FIELD: chemistry.

SUBSTANCE: invention describes an improved method forobtaining composition of the formula (II) or its salt, , by affecting compound of the formula (III) with activated derivative of propionic acid taken in the quantity of 1.3 mol per 1 mol of the compound III, and further removal of propionyl group linked to S atom from the compound of the formula IIA by effect of organic primary or secondary amine base capable of forming a water-soluble propanamide of diethanolamine or N-methylpiperazine preferentially.

EFFECT: obtaining product free from N,N-diethylpropanamide.

11 cl, 12 ex

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RU 2 333 217 C2

Authors

Kut Stiven Dzhon

Najs Rozalin Kehj

Uipperman Mark Dejvid

Dates

2008-09-10Published

2003-02-03Filed