16α,17a-ACETAL-SUBSTITUTED ANDROSTANE-17b-CARBOXYLIC ACID ESTERS OR THEIR STEREOISOMERS Russian patent published in 1997 - IPC

FIELD: organic chemistry, steroids. SUBSTANCE: products: esters of 16a, 17a-acetal-substituted androstane-17b-carboxylic acid of the general formula (I) a, or their stereoisomers where: a - H, F; b - H, F; - H, X₁-alkyl; X₂ - H, R₁-alkyl; C₁-C₄ - R₂ or C₁-C₄; R₃ - H, CR₄R₅OC(O)R₆-alkyl or phenyl; CR₄R₅OC(O)YR₆ - H, R₄; C₁-C₅ - H, linear or branched saturated or unsaturated R₅-hydrocarbon chain, CH₃-alkyl substituted with fluorine, phenyl or benzyl or radical R₆ at condition: if C₁-C₃ - H then C₁-C₄ - -alkyl. Synthesized compounds were used in medicine as antiinflammatory and antiallergic preparations. EFFECT: improved method of synthesis. 2 cl, 5 tbl