FIELD: organic chemistry, steroids. SUBSTANCE: products: esters of 16a, 17a-acetal-substituted androstane-17b-carboxylic acid of the general formula (I) a, or their stereoisomers where: a - H, F; b - H, F; 
- H, X1-alkyl; X2 - H, R1-alkyl; C1-C4 - R2 or C1-C4; R3 - H, CR4R5OC(O)R6-alkyl or phenyl; CR4R5OC(O)YR6 - H, R4; C1-C5 - H, linear or branched saturated or unsaturated R5-hydrocarbon chain, CH3-alkyl substituted with fluorine, phenyl or benzyl or radical R6 at condition: if C1-C3 - H then C1-C4 - 
-alkyl. Synthesized compounds were used in medicine as antiinflammatory and antiallergic preparations. EFFECT: improved method of synthesis. 2 cl, 5 tbl
