METHOD FOR DIFFERENTIAL DIAGNOSTICS OF MAMMARY GLAND CANCER AND CENTRAL BROKEN BREAST Russian patent published in 2008 - IPC A61B10/00 G01N33/48 

FIELD: medicine.

SUBSTANCE: examination of patient is carried out at which the following indicators are defined: social status, accompanying diseases, oncological anamnesis, blood monocytes, speed of subsidence of erythrocytes (SSE), hemoglobin, specific weight of urine, urine reaction. Then diagnostic coefficient (DC) for each indicator is defined. Social status at marker - workers diagnostic coefficient equal to (-3.5) is established in the system, at marker employees - equal to (0), at marker pupils - equal to (0), at marker the unemployed - equal to (0), at marker pensioners and disabled workers (DW) - equal to (+4). Accompanying diseases at marker - diseases of gastroenteric tract (GET) DC equal to (-5), is established in the system, at marker of disease of cardiovascular system - equal to (+5.5), at marker of disease of endocrine system - equal to (-3,5), at marker of disease of respiratory system - equal to (+2), at marker of disease of locomotor apparatus - equal to (0), at marker of disease of urogenital system - equal to (0), at marker of a combination of accompanying diseases - equal to (+8), at marker of absence of accompanying diseases - equal to (-3). Oncological anamnesis at marker - available, DC equal to (0) is established in the system, at marker absent - equal to(-1). Monocytes at marker - not present, DC equal to (0) is established in the system, at marker of 1-3% - equal to (+0.5), at marker of 4-6% - equal to (-1.5), at marker of 7-10% - equal to (+4), at marker more than 10% - equal to (0). od sedimentation rate at marker - 1-10 mm per hour DC equal to (-2.5) is established in the system, at marker of 11-20 mm per hour - equal to (-0.5), at marker of 21-30 mm per hour - equal to (+7), at marker of 31-40 mm per hour - equal to (0), at marker more than 40 mm per hour - equal to (-1). Hemoglobin at marker - less than 100 gram per l. DC equal to (0) is established in the system, at marker 100-120 gram per l. - equal to(+6), at marker more than 120 gram per l. - equal to(-4). Specific weight of urine at marker less than 1008 DC equal to (0 is established in the system, at marker 1008-1026 - equal to (-0.5), at marker more than 1026 - equal to (+6). Urine reaction at marker - sour, DC equal to (+1), is established in the system, at marker neutral - equal to (-10), at marker alkaline - equal to (0). If DC sum is from (+6) and more, diagnosis of mammary gland cancer is proved to be true, if the sum is (-12) and less, diagnosis of central broken breast is proved to be true. This way allows to differentiate cancer of mammary gland and central broken breast at the stage of laboratory examination and will be applied in early diagnostics of cancer of mammary gland, with use of such indicators as: social status, accompanying diseases, oncological anamnesis, blood monocytes, blood sedimentation rate, hemoglobin, specific weight of urine, urine reaction, it distinguish itself by availability and simplicity of calculations.

EFFECT: working out of means of diagnostics of mammary gland cancer initially.

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