FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, in particular to a method for predicting the risk of developing breast cancer in Russian women, natives of the Central Black Earth Region of Russia, based on data on interlocus interactions. Method involves analysis of polymorphic markers rs4149056 of gene SLCO1B1 – rs440837 of gene ZBTB10 – rs10454142 of gene PPP1R21. When detecting a combination of genotypes rs4149056-CC of gene SLCO1B1 – rs440837-AA of gene ZBTB10 – rs10454142-CC of gene PPP1R21, high risk of developing breast cancer is predicted.
EFFECT: invention is effective for assessing the risk of developing breast cancer based on data on interlocus interactions.
1 cl, 3 dwg, 1 ex
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