CYCLOSPORINE ANALOGUES MIXTURE AND ITS APPLICATION AS IMMUNOMODULATORY AGENT Russian patent published in 2008 - IPC C07K7/64 A61K38/13

Abstract RU 2337106 C2

FIELD: chemistry, pharmacology.

SUBSTANCE: invention relates to compositions, that include isomers mixture of cyclosporine A analogue, modified by 1,3-diene substitute in 1^st amino acid residue, where isomers represent isomers E- and Z-: , . Invention also relates to compositions application in medicine production, and to method of immunosuppression realization.

EFFECT: pharmaceutical compositions have immunosuppressive activity.

77 cl, 7 tbl, 17 dwg, 39 ex

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RU 2 337 106 C2

Authors

Najker Selvaraj

Jatskoff Rehndall U.

Foster Robert T.

Dates

2008-10-27—Published

2002-10-17—Filed