FIELD: chemistry.
SUBSTANCE: invention pertains to new method of obtaining phenylamide 5-(4-fluorophenyl)-1-[2-((2R,4R)-4-hydroxy-6-oxotetrahydropyran-2-yl)ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid (I), of the key intermediate compound in the synthesis of atorvastatin calcium, which is a hypolipidemic and/or hypocholesteremic agent. The invention also relates to methods of obtaining intermediate product and to new intermediate products.
EFFECT: perfected method of obtaining phenylamide 5-(4-fluorophenyl)-1-[2-((2R,4R)-4-hydroxy-6-oxotetrahydropyran-2-yl)ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid.
11 cl, 3 ex
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