FIELD: medicine.
SUBSTANCE: method includes definition of target HLA immunotypr, mitotic activation of unfertilised diploid oocytes after meiosis 1 by means of calcium ionophore for development blastocyst masses, each of them contains internal cellular mass (ICM), homozygous on target HLA immunotype, allocation of homozygous stem cells from ICM, plating of these cells for obtaining of lines of cells and selection of cells, homozygous on target HLA immunotype. The way obtaining of bank of these cells obtained from many donors is also described.
EFFECT: advantage of the invention lies in possibility of obtaining of considerable quantity of histocompatible cells for transplantation.
10 cl, 4 ex, 11 dwg
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