DIMERS OF PYRROL[2,1-c][1,4]BENZODIAZEPINE AS ANTITUMORAL AGENTS AND METHOD OF THEIR OBTAINING Russian patent published in 2008 - IPC C07D487/04 A61K31/5517 A61P35/00

Abstract RU 2338747 C2

FIELD: medicine.

SUBSTANCE: new derivatives of pyrrol[2,1-c][1,4]benzodiazepine of the general formula where n=2-10 are described. A pharmaceutical composition, containing them, and the method of obtaining are also described.

EFFECT: compounds possess antitumoral activity and can be applied in medicine.

18 cl, 3 ex, 2 tbl, 1 dwg

Similar patents RU2338747C2

Title	Year	Author	Number
PYRROLO[2.1-C][1.4]BENZODIAZEPINES, METHOD FOR THEIR PREPARING AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF	2003	Kamal Akhmed Ramesh Gudzhdzhar Srinivas Olepu Ramulu Poddutoori	RU2314309C2
IMIDAZODIAZEPINES, METHOD OF THEIR SYNTHESIS AND DRUG	1995	T'Erri Godel' Val'Ter Khunkeler Khajnts Shtadler Ul'Rikh Vidmer	RU2139873C1
NOVEL ANTIBODY CONJUGATES AND USES THEREOF	2014	Torgov Majkl Govard Filip Uilson	RU2684468C2
CONJUGATE ANTIBODY-DERIVATIVE OF PYRROLOBENZODIAZEPINE	2018	Kharada, Naoia Ota, Yusuke Doi, Fuminao Meguro, Masaki Khayakava, Itiro Asida, Sintszi Masuda, Takesi Nakada, Takasi Ivamoto, Mitsukhiro Kharada, Naoya Terauti, Tomoko Okatszima, Dajsuke Nakamura, Kensuke Utida, Khiroaki Khamada, Khirofumi	RU2820928C2
COMPOUNDS FOR TREATING PD-L1 DISEASES	2020	Malathong, Viengkham Fan, Pingchen Lange, Christopher Mali, Venkat Reddy Mcmurtrie, Darren J. Punna, Sreenivas Roth, Howard S. Singh, Rajinder Yang, Ju Zhang, Penglie	RU2838028C2
SECONDARY MANNOSIS FOR BACTERIAL INFECTIONS TREATMENT	2013	Ramtokhul Jiman K. Das Sandzhoj Kumar Kadijak Karolin Reddi Tkhumkunta Dzhagadisvar Vajankur Lui Gallan Mishel Lyu Bintsan Ditrikh Evelin Valle Frederik Martel Zhyulen Puasson Karl	RU2667060C2
PRODRUGS OF CONJUGATED BICYCLIC C5aR ANTAGONISTS	2019	Fan, Pingchen Lui, Rebecca M. Singh, Rajinder Mali, Venkat Reddy Zeng, Yibin Zhang, Penglie	RU2794327C2
TRIARYL COMPOUNDS FOR TREATING PD-L1 DISEASES	2020	Fan, Pingchen Lange, Christopher Mali, Venkat Reddy Mcmurtrie, Darren, J. Malathong, Viengkham Punna, Sreenivas Singh, Rajinder Yang, Ju Zeng, Yibin Zhang, Penglie	RU2840345C2
8-METHYL-1-PHENYLIMIDAZO[1,5-a]PYRAZINE COMPOUNDS	2011	Man De Adrianus Petrus Antonius Revinkel Jokhannes Bernardus Marija Jans Khristian Gerardus Jokhannes Marija Rajmakers Khans Kornelis Andreas Vejkmans Jakobus Kornelis Khenrikus Marija	RU2560162C2
QUINAZOLINE DERIVATIVES	2005	All'Gajer Khans Frestl' Vol'Fgang Koller Manuehl' Matte Anri Notsulak Joakhim Ofner Sil'Vio Oren David Razetti Vittorio Reno Zhoann Zol'Dermann Nikola Flershajm Filipp	RU2414468C2

RU 2 338 747 C2

Authors

Kamal Akhmed

Reddi Peram Surakattula Murali Mokhan

Reddi Depatla Radzhasekkhar

Dates

2008-11-20—Published

2003-03-31—Filed