THERAPEUTIC APPLICATION Russian patent published in 2008 - IPC A61K31/497 A61P35/00 A61P29/00 

Abstract RU 2340343 C2

FIELD: medicine; pharmacology.

SUBSTANCE: methods of influence of N-(3-methoxy-5-methylpyrasine-2-silt)-2-(4[1,3,4-oxadiazol-2-silt]phenyl)pyridine-3-sulphamide or its pharmaceutically comprehensible salt at treatment of a malignant neoplasm, at reduction of an atypical proliferation of malignant cells, for provocation of differentiations of malignant cells, for provocation of apoptosis in malignant cells, the way of antiangiogenic influence aimed at vessels, in blood vessels of malignant cells at a warm-blooded animal (versions), such as the person, a way of suppression of metastasises in bones and the invasion inhibitions, corresponding ways of treatment and prevention of metastasises and an invasion. The substance was known earlier as an inhibitor of endothelin-1 (ET-1).

EFFECT: efficiency on all declared applications concerning an ovary cancer.

22 cl, 2 dwg, 2 tbl

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RU 2 340 343 C2

Authors

Tondzh Devid Uill'Jam

Tejlor Sajan Toumiko

Bojl Fransis Tomas

Kh'Juz Ehndr'Ju Mark

Dzhonstoun Donna

Ashford Marianna Bernis

Barrass Najdzhel Charlz

Dates

2008-12-10Published

2003-08-20Filed