FIELD: medicine.
SUBSTANCE: for prevention of postoperative osteomyelitis use composition consisting of antimicrobial substances, dissolved in high-molecular polyvinylpyrolidone with molecular mass of 1 million. The composition is administered using a syringe into the medullar channel and in the intermuscular spaces surrounding a bone, on a measure of sealing of soft tissues after operation. Invention allows to give antimicrobial activity to tissues surrounding wound for long time at the expense of slow biodegradation of polyvinylpyrolidone and long-term diffusion of antimicrobial substances from a composition in a tissue.
EFFECT: long finding of antimicrobial substances in tissues, prevention of development of postoperative osteomyelitis.
3 tbl
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Authors
Dates
2009-01-20—Published
2006-12-12—Filed