METHOD FOR LOCAL ANTIBACTERIAL PREVENTION OF RECURRENCY IN ONE-STAGE REVISION ENDOPROSHETICS IN PATIENTS WITH PERIPROTHETIC INFECTION Russian patent published in 2021 - IPC A61B17/56 A61K31/79 A61K31/7036 A61K31/498 A61P19/00 A61P31/04 

Abstract RU 2757263 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to traumatology and orthopedics, surgery, and can be used to prevent recurrence of periprosthetic infection (PPI). The method involves the use of a polymer composition based on polyvinylpyrrolidone with antimicrobial drugs gentamicin 0.96 g and dioxidine 1.0 g. After wound closure, accumulated blood is evacuated from the joint, then the composition is injected intraarticularly through one of the channels of a two-channel venous catheter in a volume of up to 20 ml. Further administration of the composition is carried out once a day for three days.

EFFECT: creation of local antibiotic depot, prevention of formation of microbial biofilms on the surface of structures, evacuation of intra-articular fluid and administration of antimicrobial drugs, as well as reduction of the risk of developing hematomas in the area of ​​surgical intervention due to antibacterial prevention of recurrence.

1 cl, 2 ex

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RU 2 757 263 C1

Authors

Artyukh Vasilij Alekseevich

Bozhkova Svetlana Anatolevna

Panteleev Aleksandr Nikolaevich

Afanasev Aleksandr Vitalevich

Kochish Andrej Aleksandrovich

Toropov Sergej Sergeevich

Antipov Aleksandr Pavlovich

Dates

2021-10-12Published

2021-03-18Filed