REDUCTION METHOD FOR GASTROINTESTINAL TOXICITY CAUSED BY TEGAFUR Russian patent published in 2009 - IPC A61K31/513 A61K31/4412 A61K31/53 A61P35/00

Abstract RU 2348409 C2

FIELD: medicine; oncology.

SUBSTANCE: hunger patient takes up Tegafur, dihydropyrimidine dehydrogenase inhibitor and oxonic acid simultaneously.

EFFECT: intensified antineoplastic effect of Tegafur due to higher bioavailability of introduced preparations and reduced gastrointestinal toxicity ensured by higher stability of oxonic acids.

29 cl, 1 tbl, 3 ex

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RU 2 348 409 C2

Authors

Nomura Naruo

Takhara Takesi

Ambe Khirosi

Kuritani Dzun

Dates

2009-03-10—Published

2005-04-27—Filed