ANTITUMOUR AGENT CONTAINING CYTIDINE DERIVATIVE FOR CONTINUOUS INTRAVENOUS INTRODUCTION Russian patent published in 2013 - IPC A61K31/7068 A61P43/00 

Abstract RU 2471486 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to medicine, namely oncology, and may be used for treating cancer. That is ensured by the introduction of an antitumour agent containing 1-(3-C-ethinyl-β-D-ribopentofuranosyl)cytosine (ECyd) or its pharmaceutically acceptable salt into a patient by the continuous intravenous introduction at a dose of 1.30 to 8.56 mg/m2 at 1-(3-C-ethinyl-β-D-ribopentofuranosyl)cytosine for each period of introduction 2 to 336 hours.

EFFECT: method for the ECyd introduction into the patient provides a substantial therapeutic effect with provided prolonged patient's life ensured by the continuous therapy without manifested peripheral neurotoxicity caused by ECyd.

5 cl, 4 ex

Similar patents RU2471486C2

Title Year Author Number
COMBINED CHEMOTHERAPY 2001
  • Smit Mark Pirt
  • Stefens Trevor Charl'Z
RU2284818C2
COMBINED CHEMOTHERAPY 2010
  • Smit Mark Pirt
  • Stefens Trevor Charlz
RU2587013C2
COMBINED CHEMOTHERAPY 2006
  • Smit Mark Pirt
  • Stefens Trevor Charl'Z
RU2429838C2
METHOD FOR INTRODUCING EPOTILONE ANALOGS FOR TREATING CANCER CASES 2002
  • Bandiopadkhiaj Rebanta
  • Mehlloj Timoti M.
  • Panaggio Andrea
  • Ragkhavan Krishnasvami Srinivas
  • Vehria Sehjlesh Ehmilal
RU2292202C2
COMBINED APPLICATION OF ECTEINASCIDIN-743 AND PLATINUM-CONTAINING ANTI-TUMOUR COMPOUNDS 2004
  • D'Inkal'Chi Mauritsio
  • Dzhanni Luka
  • Dzhavatstsi Rafaehlla
  • Garsija Martin Margarita
  • Dzhadson Jan
  • Khimeno Don'Jake Khose Marija
  • Sessa Krist'Jana
RU2391101C2
NEW DERIVATIVES OF PEG 2015
  • Fukushima, Masakazu
  • Eshima, Kiyoshi
RU2697551C2
COMBINATION OF TRIFLURIDINE/TIPIRACIL HYDROCHLORIDE, ANTITUMOR PLATINUM COMPLEX, AND MODULATOR OF CONTROL POINTS OF IMMUNE RESPONSE 2018
  • Abastado Jean-Pierre
  • Amellal Nadia
  • Bruno Alain
  • Burbridge Michael Frank
  • Cattan Valerie
  • Leger Catherine
RU2778887C2
METHODS AND COMPOSITIONS FOR TREATING CANCER 2009
  • Burger Angelika
  • Khendriks Khans
  • Rademaker Bernardus
RU2508116C2
METHODS OF APPLYING (+)-1,4-DIHYDRO-7-[(3S, 4S)-3-METHOXY-4-(METHYLAMINO)-1-PYRROLIDINYL]-4-OXO-1-(THIAZOLYL)-1,8-NAPHTHIRIDINE-3-CARBOXYLIC ACID FOR CANCER TREATMENT 2006
  • Ejdelman Deniel S.
  • Silverman Dzheffri A.
  • Arkin Majkl
  • Khajd Dzhennifer
  • Uolker Dunkan
  • Rajt Zhasmin
RU2592231C2
ANTICANCER THERAPY USING COMPOUNDS OF 3,5-DISUBSTITUTED BENZENE ALKYNYL AND PEMBROLIZUMAB 2020
  • Yonekura, Kazuhiko
  • Hirai, Hiroshi
  • Matsuoka, Kazuaki
RU2822064C2

RU 2 471 486 C2

Authors

Kazuno Khiromi

Koizumi Katsukhisa

Mita Akira

Dates

2013-01-10Published

2008-04-04Filed