N-[HETEROARYL(PIPERIDINE-2-YL)METHYL]BENZAMIDE DERIVATIVES AND APPLICATION IN THERAPY Russian patent published in 2009 - IPC C07D417/06 C07D401/06 C07D409/06 A61K31/445 A61P25/00

Abstract RU 2351596 C2

FIELD: chemistry.

SUBSTANCE: invention refers to new compounds of general formula (I): (I) where: R₁ represents either direct or branched (C₁-C₇)alkyl, or (C₂-C₄)alkenyl; R₂ represents piridinyl, thienyl, thiazol; R₃ represents one or more substitutes chosen from halogen atoms and following groups; trifluoromethyl, direct or branched (C₁-C₆)alkyl; as free base or additive salt with acid. Additionally, the invention concerns medical product, pharmaceutical composition, and application.

EFFECT: production of new biologically active compounds active to specific inhibitors of glycine glyt 1 and/or glyt 2 carriers.

6 cl, 2 ex, 1 tbl

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RU 2 351 596 C2

Authors

Dargazanli Zhiad

Ehstenn-Butu Zhenev'Ev

Medesko Florans

Renon Marija-Karmen

Dates

2009-04-10—Published

2004-10-15—Filed