N-PHENYL(PIPERIDINE-2-YL)METHYL-BENZAMIDE DERIVATIVES, AND THEIR APPLICATION IN THERAPY Russian patent published in 2009 - IPC C07D211/26 C07D401/12 C07D403/12 C07D409/12 A61K31/445 A61P25/00

Abstract RU 2351588 C2

FIELD: chemistry.

SUBSTANCE: invention refers to new compounds satisfying general formula (I): where: R₁ stands for direct or branched (C₁-C₇)alkyl, X stands for hydrogen atom, R₂ stands for the group chosen from naphthalenyl, pyridinyl, isoquinoleinyl, thienyl, imidazolyl, benzothienyl, benzimidazolyl, indolyl, benzotriazolyl and optionally substituted with one or more substitutes chosen from halogen atoms and following groups: (C₁-C₄)alkyls, thio(C₁-C₄)alkyls or phenyls, optionally substituted with one or more substitutes chosen from halogen atoms or trifluoromethyl, as free base or additive salt with acid. Additionally, the invention concerns medical product, pharmaceutical composition, and application.

EFFECT: production of new biologically active compounds active to specific inhibitors of glycine glyt 1 and/or glyt 2 carriers.

6 cl, 3 ex, 1 tbl

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RU 2 351 588 C2

Authors

Dargazanli Zhiad

Ehstenn-Butu Zhenev'Ev

Maga Paskal'

Dates

2009-04-10—Published

2004-10-15—Filed