COMPOUND ANTAGONIST VEGF AND ANTIPROLIFERATIVE AGENT Russian patent published in 2009 - IPC A61K31/00 A61K39/395 A61K38/17 A61K31/337 A61K33/24 A61P35/00

Abstract RU 2353353 C2

FIELD: medicine.

SUBSTANCE: there is disclosed application of compound antagonist VEGF representing VEGFR1R2-FcΔCl(a) or Flt1D2. Flk1D3. FcΔCl (a) and antiproliferative agent: paclitaxel, docetaxel, or cisplatin, carboplatin, iproplatin for making a medical product for cancer treatment and/or tumour growth reduction or inhibition in an indigent person (versions), relevant method, pharmaceutical composition and a kit for cancer treatment.

EFFECT: overtotal effect of the disclosed combination (97% tumour suppression) observed without any by-effects.

10 cl, 2 dwg, 1 tbl

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RU 2 353 353 C2

Authors

Khoulash Dzhoslin

Dzhaff Robert

Khu Limin'

Jankopulos Dzhordzh D.

Dates

2009-04-27—Published

2004-07-23—Filed