PREGABALIN DERIVATIVES FOR HOT FLUSH TREATMENT Russian patent published in 2009 - IPC A61K31/197 A61P25/24 A61P25/08 A61P25/00 

Abstract RU 2353358 C2

FIELD: medicine.

SUBSTANCE: invention refers to medicine, particularly to hot flush treatment in mammals, including human. Method involves (3S,5R)-3-aminomethyl-5-methyloctane acid or its pharmaceutically acceptable salt introduced in the patient organism in effective amount.

EFFECT: method provides treatment of moderate and severe vasomotor symptoms, including in post menopause in women, ensured by predominant high activity of the acid as alpha-2-delta ligand.

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RU 2 353 358 C2

Authors

Duli Dehvid Dzhejms

Tehjlor Charl'Z Prajs Ml.

Torp Ehndrju Dzhon

Vustrou Dehvid Jurgen

Dates

2009-04-27Published

2003-12-03Filed