DIAZASPIROPIPERIDINE DERIVATIVES Russian patent published in 2009 - IPC C07D471/10 A61K31/438 A61P25/00 A61P25/18 

Abstract RU 2355690 C2

FIELD: chemistry.

SUBSTANCE: invention concerns novel derivatives of diazaspiropiperidine of the formula I: , where A-B is -CH2-CH2-, -CH2-O- or -O-CH2-; X is hydrogen or hydroxy; R1 is aryl optionally substituted by one or more substitutes selected out of group including haloid, (lower) alkyl, cyano, CF3, -OCF3, (lower) alkoxy, -SO2-(lower)alkyl, or heteroaryl with two nitrogen atoms; R2 is phenyl optionally substituted by one or more substitutes selected out of group including haloid, (lower) alkyl, CF3 or (lower) alkoxy; R3 is hydrogen or (lower)alkyl; n is 0, 1 or 2; and their pharmaceutically acceptable salts.

EFFECT: medicine based on compounds of the formula 1 and their application in obtaining medicine for neuropathological and neuropsychiatric disease treatment.

12 cl, 1 tbl, 29 ex

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RU 2 355 690 C2

Authors

Chekkarelli Simona-Marija

Kholidon Sinese

Pinar Ehmman'Juehl'

Tomas Ehndr'Ju Uill'Jam

Dates

2009-05-20Published

2004-12-30Filed