CHRONIC CARDIAL INSUFFICIENCY COURSE PREDICTION METHOD Russian patent published in 2009 - IPC G01N33/48 G01N33/53 

FIELD: medicine.

SUBSTANCE: invention refers to cardiology, particularly to prediction of clinical course of chronic cardiac insufficiency. The method is ensured by evaluating whole blood samples for CD133⁺-cells thereafter analysed for colony-formation ability when cultivated in vitro. Risk of unfavourable outcome, including early death and/or hospitalisation is highest, if examination of the patient suffering from chronic cardiac insufficiency shows representation of CD133⁺-cells in whole blood is 1×10⁵/l or less, while colony-formation units are total 2/mm² or less. The favourable outcome is predicted, if representation of CD133⁺-cells in whole blood is 1×10⁵/l or more and number of colony-formation units is 2/mm² or more.

EFFECT: application of the invention allows for high-reliable prediction of unfavourable clinical course of chronic cardiac insufficiency.

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