METHOD OF FORECASTING INFINTILE CEREBRAL PARALYSES IN MATURE BABIES Russian patent published in 2009 - IPC A61B5/00 

FIELD: medicine.

SUBSTANCE: invention pertains to medicine, namely, to pediatric neurology, and may be used for forecasting infantile cerebral paralyses in mature babies. Duration of prolonged artificial lung ventilation is detected. Duration of waterless period, Apgar scores, use of dopamine or adrenaline, seduxen within the first 1-7 days of live; intubation of trachea, carried out mask artificial lung ventilation in the labour ward, application of valporic acid within 1-30 days of live are evaluated. Each of the evaluated aspect is assigned diagnostic coefficients according to decreasing informative value, namely, in case of application of dopamine or adrenaline within first 1-7 days of live diagnostic coefficient equals 0.78, if they were not used diagnostic coefficient equals (-)0.14; in case of seduxen use in first 1-7 days of live set diagnostic coefficient equals 0.33, if it was not used - diagnostic coefficient equals (-)0.30; if valporic acid was used within first 1-30 days of live diagnostic coefficient equals 0.95, if it was not used - (-)0.10; if mask artificial lung ventilation was applied in the labor ward - diagnostic coefficient equals 0.26, in its absence diagnostic coefficient equals (-)0.38; if duration of waterless period is ≥ 30 hours diagnostic coefficient equals 0.67, if duration of waterless period is < 30 hours diagnostic coefficient equals (-)0.13; with intubation performed in the labour ward diagnostic coefficient equals 0.26, without it (-)0.33; with Apgar score on the 1^st minute < 4 scores - diagnostic coefficient makes 0.31, with Apgar score ≥ 4 scores, diagnostic coefficient equals (-)0.20; with duration of artificial lung ventilation ≥ 5 days diagnostic coefficient equals 0.14, with duration of artificial lung ventilation < 5 days diagnostic coefficient equals (-)0.03. Thereafter total of diagnostic coefficients starting with correction equal to (-)0.176 is calculated. Decision of relating the baby to the group of infantile cerebral paralyses is made, If total of diagnostic coefficients according to the decrease of informative value at a certain increment of analyses is not less than 0.68, and to the group of not infantile cerebral paralyses, if total of diagnostic coefficients equals or is less than (-)1.2.

EFFECT: method makes it possible to forecast formation of ICP on the 30^th day, thus decreasing probability of disability in immature babies as a result of early modification of the approach to treatment and follow up.

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