FIELD: chemistry.
SUBSTANCE: invention can be applied in medicine and concerns inhibitors of MaR-kinase p38 of formula 
where W represents N or O, when Y represents C, and W represents C, when Y represents N; U represents CH or N; V represents C-E or N; X represents O, S, SO, SO2, NH, C=O,-C=NOR1 or CHOR1; B represents H or NH2; R1, E and A stands for H or various alkyl, heteroalkyl, aromatic and heteroaromatic substitutes.
EFFECT: production of new biologically active compounds.
48 cl, 138 ex, 54 dwg
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