METHOD FOR MAKING INACTIVATED EMULSIFIED AVIAN INFLUENZA VACCINE AND INACTIVATED EMULSIFIED AVIAN INFLUENZA VACCINE Russian patent published in 2009 - IPC A61K39/135 C12N7/00 

Abstract RU 2358760 C1

FIELD: medicine; veterinary science.

SUBSTANCE: method involves preparation of antigen material from avian influenza virus strain thereafter cleaned from ballast impurity, virus inactivation, mixing of antigen material and oil adjuvant with controlling the end product. The avian influenza virus strain is represented with the strain "Primorsky" of avian influenza virus referred to Orthomyxoviridae family, Influenzae virus avicum type of serotype A, subtype H5N2, collection Federal State Institurion VGNKI, serial №129 - "ДЕП". The vaccine made under the given method, contains cleaned and avirulent antigen material from strain " Primorsky" and oil adjuvant in ratio (wt %): antigen material - 30.0-40.0, oil adjuvant - 60.0-70.0.

EFFECT: decreased labour and power inputs in making the vaccine and improved quality of antigen material, high antigen activity of the vaccine and effective protection of susceptible poultry from epizootic virus of subtype H5.

14 cl, 5 tbl, 6 ex

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RU 2 358 760 C1

Authors

Borisov Aleksandr Vladimirovich

Lozovoj Dmitrij Anatol'Evich

Smolenskij Vladimir Ivanovich

Okhapkin Sergej Sergeevich

Drygin Vladimir Viktorovich

Jablochkin Nikolaj Aleksandrovich

Dorokhin Vladimir Vasil'Evich

Litenkova Irina Jur'Evna

Rakhmanin Pavel Petrovich

Krjukov Sergej Veniaminovich

Trenev Vasilij Nikolaevich

Solov'Ev Boris Vasil'Evich

Dates

2009-06-20Published

2008-03-17Filed