FIELD: veterinary science; biotechnology.
SUBSTANCE: invention refers to veterinary virology and biotechnology and concerns a novel strain of influenza type A subtype H9 of Orthomyxoviridae family, genus Alphainfluenzavirus, deposited in the collection of FGBI "ARRIAH" under registration number: No. 333 — dep/20-121 — SCMS FGBU "ARRIAH". Proposed strain is reproduced in 11-day-old chicken embryos of SPF chickens, where it reaches an infectious titre of not less than 8.5 lg EID50/cm3. In the composition of the inactivated vaccine, the strain has pronounced antigenic and immunogenic properties, inducing production of specific antibodies trapped in ELISA and RTGA.
EFFECT: disclosed strain can be used to control antigenic and immunogenic activity of avian influenza vaccines, as well as for preparing biopreparations for diagnosis and specific prevention of avian influenza type A subtype H9.
1 cl, 5 tbl, 1 dwg, 5 ex
| Title | Year | Author | Number |
|---|---|---|---|
| STRAIN "A/CHICKEN/PRIMORSK/419/2018 H9N2" OF AVIAN INFLUENZA VIRUS OF GENUS ALPHAINFLUENZAVIRUS TYPE INFLUENZA A VIRUS SUBTYPE H9 FOR CONTROLLING ANTIGENIC AND IMMUNOGENIC ACTIVITY OF VACCINES FOR AVIAN INFLUENZA AND FOR MAKING BIOPREPARATIONS FOR DIAGNOSIS AND SPECIFIC PREVENTION OF AVIAN INFLUENZA TYPE A SUBTYPE H9 | 2020 |
|
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|
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| STRAIN A/GOOSE/KALMYKIA/813/16 H5N8 VIRUS AVICUM BIRD INFLUENZA VIRUS AVICUM INFLUENZA TYPE A AND SUBSTITUTE H5 FOR CONTROL OF ANTIGEN AND IMMUNIZING ACTIVITY OF VACCINE AGAINST AVIAN INFLUENZA AND FOR THE MANUFACTURE OF BIOPREPARATIONS FOR DIAGNOSTICS AND SPECIFIC PREVENTION OF INFLUENZA BIRDS OF TYPE A OF SUBSTITUTE H5 | 2017 |
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