DIAGNOSTICUM AND TEST-SYSTEM FOR DETERMINING ACTIVITY OF ANTI-RABIES SERUMS AND PREPARATON OF HETEROLOGICAL ANTI-RABIES IMMUNOGLOBULIN IN VITRO BY DOT-IMMUNOANALYSIS METHOD Russian patent published in 2009 - IPC G01N33/532 

FIELD: biotechnologies.

SUBSTANCE: claimed is test-system for determining specific activity of anti-rabies serums and immunoglobulin. Test-system contains nitrocellulose membrane with applied on its surface positive (branch standard sample of anti-rabies immunoglobulin specific activity) and negative (normal horse serum) controls, de-ionised water for washings, sample dilution, conjugate and development (visualisation) system. As conjugate, used is gold hydrosol with particle size 15-17 nm, sorptially connected with inactivated fixed rabies virus of production strain "Moskva-3253" from rabbit virus-containing brain suspension or rabies virus glycoproteide.

EFFECT: extending possibility of determining anti-rabies serum and immunoglobulin specific activity in production of heterological anti-rabies immunoglobulin.

6 cl, 2 tbl, 2 ex