FIELD: virology, veterinary, in particular method for titration of virus-neutralizing antibodies to rhabdovirus in blood serum of vaccinated animals.
SUBSTANCE: claimed method includes interaction of vaccine rhabdovirus of specific strain with target sera; incubation of obtained mixture containing virus and serum for 60 min at 37°C; daily intact culture of saiga kidney is introduced, mixture is fed into CO2-incubator and is hold for 5-7 days. Then virus-neutralizing antibodies is determined based on limit serum dilution wherein 50 % of virus cytopathicitic action on cell culture is suppressed.
EFFECT: more sensitive and economical method antirabic virus-neutralizing antibody titration.
2 tbl, 2 ex
| Title | Year | Author | Number |
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| METHOD OF ASSAY OF ANTIRABIES VIRUS-NEUTRALIZING ANTIBODIES | 1997 |
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