FIELD: chemistry; medicine.
SUBSTANCE: in novel spiropentacyclic compounds of formula (I) 
R1 and R2 collectively with nitrogen atom, to which they are bound, form 6-member monocyclic saturated heterocyclic ring, which can optionally contain 1 additional O or N; R3 represents hydrogen, halogen or lower alkyl; R4 and R5 each independently represents halogen; and X represents -C(O)- or -SO2-; or their pharmaceutically acceptable salts, intended for application as therapeutically active substances for treatiment and/or prevention of diseases connected with modulation of CB1 receptors and also pharmaceutical composition based on said compounds.
EFFECT: novel compounds possess useful biological properties.
12 cl, 1 tbl, 6 ex
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