METHOD OF DIFFERENTIAL DIAGNOSTICS OF POLYNEUROPATHY OF VIBRATION GENESIS AND DIABETIC POLYNEUROPATHY Russian patent published in 2009 - IPC A61B5/476 A61B5/484 A61B5/488 

FIELD: medicine.

SUBSTANCE: invention relates to field of medicine, namely, to neurology and professional pathology. Electroencephalography (EEG) with registration of long-latent acoustic induced potentials (LAIP), electroneuromyography (ENMG), algesimetry are performed and diagnostic index for polyneuropathy of vibration genesis (F₁) and diagnostic index for diabetic polyneuropathy (F2) are calculated by formulas: F₁=-5.40+3.63·A₁+1.67·A₂-5.89·A₃-1.33·A₄+0.31·A₅-0.57·A₆+0.39·A₇·0.5·A₈+0.73·A9-0.61·A₁₀; F₂=-15.53-5.39·A₁-12.32·A₂+5.69·A₃-8.98·A₄ 1.69·A₅+4.97·A₆+2.09·A₇+1.32·A₈-0.91·A₉+0.76·A₁₀, where -5.40 and -15.53 - constants; 3.63; 1.67; 5.89; 1.33; 0.31; 0.57; 0.39; 0.5; 0.73; 0.61; 5.39; 12.32; 5.69; 8.98; 1.69; 4.97; 2.09; 1.32; 0.91; 0.76 - discrimination coefficients; A₁ - index of algesimetry on second phalanx of second finger of right hand in mm; A₂ - amplitude of sensory response of tibial nerve in mcV; A₃ - amplitude of sensory response of ulner nerve in mcV; A₄ - motor rate on section wrist-elbow of ulner nerve in m/sec; A₅ - presence or absence of low-amplitude EEG in LAIP recording present - 1; absent - 0; A₆ - sensory rate of tibial nerve in m/sec; A₇ - index of amplitude P2-N2 of LAIP in right temporal lead, A₈ - index of delta activity at LAIP registration in per cent; A₉ - left-side asymmetry in tetta-subrange in frontal leads present - 0; absent - 1; A₁₀ - index of amplitude P2-N2 of LAIP in left temporal lead If F₁ is larger or equal F₂ polyneuropathy of vibration genesis is diagnosed, if F₁ is less than F₂ diabetic polyneuropathy is diagnosed.

EFFECT: extension of arsenal of means for differential diagnostics of polyneuropathy of vibration genesis and diabetic polyneuropathy

3 ex, 1 tbl